5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers

DNA modifications such as 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are epigenetic marks known to affect global gene expression in mammals. Given their prevalence in the human genome, close correlation with gene expression and high chemical stability, these DNA epigenetic marks could...

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Bibliografiska uppgifter
I publikationen:Cell Res
Huvudupphovsmän: Li, Wenshuai, Zhang, Xu, Lu, Xingyu, You, Lei, Song, Yanqun, Luo, Zhongguang, Zhang, Jun, Nie, Ji, Zheng, Wanwei, Xu, Diannan, Wang, Yaping, Dong, Yuanqiang, Yu, Shulin, Hong, Jun, Shi, Jianping, Hao, Hankun, Luo, Fen, Hua, Luchun, Wang, Peng, Qian, Xiaoping, Yuan, Fang, Wei, Lianhuan, Cui, Ming, Zhang, Taiping, Liao, Quan, Dai, Menghua, Liu, Ziwen, Chen, Ge, Meckel, Katherine, Adhikari, Sarbani, Jia, Guifang, Bissonnette, Marc B, Zhang, Xinxiang, Zhao, Yupei, Zhang, Wei, He, Chuan, Liu, Jie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630683/
https://ncbi.nlm.nih.gov/pubmed/28925386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.121
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