5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers

DNA modifications such as 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are epigenetic marks known to affect global gene expression in mammals. Given their prevalence in the human genome, close correlation with gene expression and high chemical stability, these DNA epigenetic marks could...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Res
Egile Nagusiak: Li, Wenshuai, Zhang, Xu, Lu, Xingyu, You, Lei, Song, Yanqun, Luo, Zhongguang, Zhang, Jun, Nie, Ji, Zheng, Wanwei, Xu, Diannan, Wang, Yaping, Dong, Yuanqiang, Yu, Shulin, Hong, Jun, Shi, Jianping, Hao, Hankun, Luo, Fen, Hua, Luchun, Wang, Peng, Qian, Xiaoping, Yuan, Fang, Wei, Lianhuan, Cui, Ming, Zhang, Taiping, Liao, Quan, Dai, Menghua, Liu, Ziwen, Chen, Ge, Meckel, Katherine, Adhikari, Sarbani, Jia, Guifang, Bissonnette, Marc B, Zhang, Xinxiang, Zhao, Yupei, Zhang, Wei, He, Chuan, Liu, Jie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630683/
https://ncbi.nlm.nih.gov/pubmed/28925386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.121
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