Mettl3-/Mettl14-mediated mRNA N(6)-methyladenosine modulates murine spermatogenesis

Spermatogenesis is a differentiation process during which diploid spermatogonial stem cells (SSCs) produce haploid spermatozoa. This highly specialized process is precisely controlled at the transcriptional, posttranscriptional, and translational levels. Here we report that N(6)-methyladenosine (m(6...

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Gepubliceerd in:Cell Res
Hoofdauteurs: Lin, Zhen, Hsu, Phillip J, Xing, Xudong, Fang, Jianhuo, Lu, Zhike, Zou, Qin, Zhang, Ke-Jia, Zhang, Xiao, Zhou, Yuchuan, Zhang, Teng, Zhang, Youcheng, Song, Wanlu, Jia, Guifang, Yang, Xuerui, He, Chuan, Tong, Ming-Han
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630681/
https://ncbi.nlm.nih.gov/pubmed/28914256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.117
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