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Solution structure of the RNA recognition domain of METTL3-METTL14 N(6)-methyladenosine methyltransferase

N(6)-methyladenosine (m(6)A), a ubiquitous RNA modification, is installed by METTL3-METTL14 complex. The structure of the heterodimeric complex between the methyltransferase domains (MTDs) of METTL3 and METTL14 has been previously determined. However, the MTDs alone possess no enzymatic activity. He...

詳細記述

保存先:
書誌詳細
出版年:Protein Cell
主要な著者: Huang, Jinbo, Dong, Xu, Gong, Zhou, Qin, Ling-Yun, Yang, Shuai, Zhu, Yue-Ling, Wang, Xiang, Zhang, Delin, Zou, Tingting, Yin, Ping, Tang, Chun
フォーマット: Artigo
言語:Inglês
出版事項: Higher Education Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418081/
https://ncbi.nlm.nih.gov/pubmed/29542011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-018-0518-7
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