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Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)
Hepatic mitochondria play a central role in the regulation of intermediary metabolism and maintenance of normoglycemia, and there is great interest in assessing rates of hepatic mitochondrial citrate synthase flux (V(CS)) and pyruvate carboxylase flux (V(PC)) in vivo. Here, we show that a positional...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5630596/ https://ncbi.nlm.nih.gov/pubmed/28986525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01143-w |
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