Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study

BACKGROUND: Preclinical and postmortem studies have implicated the metabotropic glutamate receptor 5 (mGluR5) in the pathophysiology of major depressive disorder (MDD). The goal of the present study was to determine the role of mGluR5 in a large group of individuals with MDD compared to healthy cont...

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Veröffentlicht in:Biol Psychiatry Cogn Neurosci Neuroimaging
Hauptverfasser: Abdallah, Chadi G., Hannestad, Jonas, Mason, Graeme F., Holmes, Sophie E., DellaGioia, Nicole, Sanacora, Gerard, Jiang, Lihong, Matuskey, David, Satodiya, Ritvij, Gasparini, Fabrizio, Lin, Xin, Javitch, Jonathan, Planeta, Beata, Nabulsi, Nabeel, Carson, Richard E., Esterlis, Irina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630181/
https://ncbi.nlm.nih.gov/pubmed/28993818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpsc.2017.03.019
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