Identification of senescent cell surface targetable protein DPP4

Senescent cell accumulation in aging tissues is linked to age-associated diseases and declining function, prompting efforts to eliminate them. Mass spectrometry analysis revealed that DPP4 (dipeptidyl peptidase 4) was selectively expressed on the surface of senescent, but not proliferating, human di...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Kim, Kyoung Mi, Noh, Ji Heon, Bodogai, Monica, Martindale, Jennifer L., Yang, Xiaoling, Indig, Fred E., Basu, Sandip K., Ohnuma, Kei, Morimoto, Chikao, Johnson, Peter F., Biragyn, Arya, Abdelmohsen, Kotb, Gorospe, Myriam
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630018/
https://ncbi.nlm.nih.gov/pubmed/28877934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.302570.117
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