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SCAMP4 enhances the senescent cell secretome

The senescence-associated secretory phenotype (SASP) is a major trait of senescent cells, but the molecular regulators of SASP factor secretion are poorly understood. Mass spectrometry analysis revealed that secretory carrier membrane protein 4 (SCAMP4) levels were strikingly elevated on the surface...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Kim, Kyoung Mi, Noh, Ji Heon, Bodogai, Monica, Martindale, Jennifer L., Pandey, Poonam R., Yang, Xiaoling, Biragyn, Arya, Abdelmohsen, Kotb, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075036/
https://ncbi.nlm.nih.gov/pubmed/29967290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.313270.118
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