Identification of senescent cell surface targetable protein DPP4

Senescent cell accumulation in aging tissues is linked to age-associated diseases and declining function, prompting efforts to eliminate them. Mass spectrometry analysis revealed that DPP4 (dipeptidyl peptidase 4) was selectively expressed on the surface of senescent, but not proliferating, human di...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Kim, Kyoung Mi, Noh, Ji Heon, Bodogai, Monica, Martindale, Jennifer L., Yang, Xiaoling, Indig, Fred E., Basu, Sandip K., Ohnuma, Kei, Morimoto, Chikao, Johnson, Peter F., Biragyn, Arya, Abdelmohsen, Kotb, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630018/
https://ncbi.nlm.nih.gov/pubmed/28877934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.302570.117
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