Neutral tumor evolution in myeloma is associated with poor prognosis

Recent studies suggest that the evolutionary history of a cancer is important in forecasting clinical outlook. To gain insight into the clonal dynamics of multiple myeloma (MM) and its possible influence on patient outcomes, we analyzed whole exome sequencing tumor data for 333 patients from Myeloma...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Johnson, David C., Lenive, Oleg, Mitchell, Jonathan, Jackson, Graham, Owen, Roger, Drayson, Mark, Cook, Gordon, Jones, John R., Pawlyn, Charlotte, Davies, Faith E., Walker, Brian A., Wardell, Christopher, Gregory, Walter M., Cairns, David, Morgan, Gareth J., Houlston, Richard S., Kaiser, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630010/
https://ncbi.nlm.nih.gov/pubmed/28827410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-750612
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