Neutral tumor evolution in myeloma is associated with poor prognosis

Recent studies suggest that the evolutionary history of a cancer is important in forecasting clinical outlook. To gain insight into the clonal dynamics of multiple myeloma (MM) and its possible influence on patient outcomes, we analyzed whole exome sequencing tumor data for 333 patients from Myeloma...

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Publicado en:Blood
Autores principales: Johnson, David C., Lenive, Oleg, Mitchell, Jonathan, Jackson, Graham, Owen, Roger, Drayson, Mark, Cook, Gordon, Jones, John R., Pawlyn, Charlotte, Davies, Faith E., Walker, Brian A., Wardell, Christopher, Gregory, Walter M., Cairns, David, Morgan, Gareth J., Houlston, Richard S., Kaiser, Martin F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2017
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630010/
https://ncbi.nlm.nih.gov/pubmed/28827410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-750612
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