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The Prion-Like Behavior of Assembled Tau in Transgenic Mice

Tauopathies constitute neurodegenerative diseases that are characterized by the intracellular deposition of filaments made of hyperphosphorylated tau protein. The pattern of tau deposition in Alzheimer’s disease follows a stereotypical progression, with the first lesions appearing in the locus coeru...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Clavaguera, Florence, Tolnay, Markus, Goedert, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629990/
https://ncbi.nlm.nih.gov/pubmed/27940600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024372
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