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The Prion-Like Behavior of Assembled Tau in Transgenic Mice

Tauopathies constitute neurodegenerative diseases that are characterized by the intracellular deposition of filaments made of hyperphosphorylated tau protein. The pattern of tau deposition in Alzheimer’s disease follows a stereotypical progression, with the first lesions appearing in the locus coeru...

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Bibliografische gegevens
Gepubliceerd in:Cold Spring Harb Perspect Med
Hoofdauteurs: Clavaguera, Florence, Tolnay, Markus, Goedert, Michel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629990/
https://ncbi.nlm.nih.gov/pubmed/27940600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024372
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