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The Prion-Like Behavior of Assembled Tau in Transgenic Mice

Tauopathies constitute neurodegenerative diseases that are characterized by the intracellular deposition of filaments made of hyperphosphorylated tau protein. The pattern of tau deposition in Alzheimer’s disease follows a stereotypical progression, with the first lesions appearing in the locus coeru...

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Vydáno v:Cold Spring Harb Perspect Med
Hlavní autoři: Clavaguera, Florence, Tolnay, Markus, Goedert, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629990/
https://ncbi.nlm.nih.gov/pubmed/27940600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024372
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