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“Prion‐Like” Templated Misfolding in Tauopathies

The soluble microtubule‐associated protein tau forms hyperphosphorylated, insoluble and filamentous inclusions in a number of neurodegenerative diseases referred to as “tauopathies.” In Alzheimer's disease, tau pathology develops in a stereotypical manner, with the first lesions appearing in th...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Clavaguera, Florence, Lavenir, Isabelle, Falcon, Ben, Frank, Stephan, Goedert, Michel, Tolnay, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028860/
https://ncbi.nlm.nih.gov/pubmed/23587140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12044
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