A Combination of Recombinant Mycobacterium bovis BCG Strains Expressing Pneumococcal Proteins Induces Cellular and Humoral Immune Responses and Protects against Pneumococcal Colonization and Sepsis

Pneumococcal diseases remain a substantial cause of mortality in young children in developing countries. The development of potentially serotype-transcending vaccines has been extensively studied; ideally, such a vaccine should include antigens that are able to induce protection against colonization...

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Vydáno v:Clin Vaccine Immunol
Hlavní autoři: Goulart, Cibelly, Rodriguez, Dunia, Kanno, Alex I., Converso, Thiago Rojas, Lu, Ying-Jie, Malley, Richard, Leite, Luciana C. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629666/
https://ncbi.nlm.nih.gov/pubmed/28768668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00133-17
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