Early pneumococcal clearance in mice induced by systemic immunization with recombinant BCG PspA-PdT prime and protein boost correlates with cellular and humoral immune response in bronchoalveolar fluids (BALF)

An effective immunological response in the lungs during a pneumococcal infection is a key factor to the bacteria clearance and prevention of sepsis. In order to develop broad-range pneumococcal vaccines several pneumococcal proteins and strong adjuvants have been investigated. Previously, we constru...

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Detalhes bibliográficos
Publicado no:Vaccine X
Main Authors: Goulart, Cibelly, Rodriguez, Dunia, Kanno, Alex I., Silva, José Lourenço S.C., Leite, Luciana C.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Regular paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928339/
https://ncbi.nlm.nih.gov/pubmed/31891153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvacx.2019.100049
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