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Predicting Amino Acid Substitution Probabilities Using Single Nucleotide Polymorphisms

Fast genome sequencing offers invaluable opportunities for building updated and improved models of protein sequence evolution. We here show that Single Nucleotide Polymorphisms (SNPs) can be used to build a model capable of predicting the probability of substitution between amino acids in variants o...

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Veröffentlicht in:Genetics
Hauptverfasser: Rizzato, Francesca, Rodriguez, Alex, Biarnés, Xevi, Laio, Alessandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629329/
https://ncbi.nlm.nih.gov/pubmed/28754661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300078
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