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Non-Markovian effects on protein sequence evolution due to site dependent substitution rates
BACKGROUND: Many models of protein sequence evolution, in particular those based on Point Accepted Mutation (PAM) matrices, assume that its dynamics is Markovian. Nevertheless, it has been observed that evolution seems to proceed differently at different time scales, questioning this assumption. In...
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| Izdano u: | BMC Bioinformatics |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4921000/ https://ncbi.nlm.nih.gov/pubmed/27342318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1135-1 |
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