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The Yeast Heterochromatin Protein Sir3 Experienced Functional Changes in the AAA+ Domain After Gene Duplication and Subfunctionalization

A key unresolved issue in molecular evolution is how paralogs diverge after gene duplication. For multifunctional genes, duplication is often followed by subfunctionalization. Subsequently, new or optimized molecular properties may evolve once the protein is no longer constrained to achieve multiple...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Hanner, Ashleigh S., Rusche, Laura N.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629320/
https://ncbi.nlm.nih.gov/pubmed/28827288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300180
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