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The Duplicated Deacetylases Sir2 and Hst1 Subfunctionalized by Acquiring Complementary Inactivating Mutations
Protein families are generated by successive rounds of gene duplication and subsequent diversification. However, the paths by which duplicated genes acquire distinct functions are not well characterized. We focused on a pair of duplicated deacetylases from Saccharomyces cerevisiae, Sir2 and Hst1, th...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147794/ https://ncbi.nlm.nih.gov/pubmed/21690292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05175-11 |
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