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The Duplicated Deacetylases Sir2 and Hst1 Subfunctionalized by Acquiring Complementary Inactivating Mutations

Protein families are generated by successive rounds of gene duplication and subsequent diversification. However, the paths by which duplicated genes acquire distinct functions are not well characterized. We focused on a pair of duplicated deacetylases from Saccharomyces cerevisiae, Sir2 and Hst1, th...

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Bibliografski detalji
Glavni autori: Froyd, Cara A., Rusche, Laura N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147794/
https://ncbi.nlm.nih.gov/pubmed/21690292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05175-11
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