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Transcriptional silencing functions of the yeast protein Orc1/Sir3 subfunctionalized after gene duplication

The origin recognition complex (ORC) defines origins of replication and also interacts with heterochromatin proteins in a variety of species, but how ORC functions in heterochromatin assembly remains unclear. The largest subunit of ORC, Orc1, is particularly interesting because it contains a nucleos...

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Detalhes bibliográficos
Main Authors: Hickman, Meleah A., Rusche, Laura N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984160/
https://ncbi.nlm.nih.gov/pubmed/20974972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006436107
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