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Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration

The reversibility and strength of the previously established dimerization of the important glycopeptide antibiotic vancomycin in four different aqueous solvents (including a medically-used formulation) have been studied using short-column sedimentation equilibrium in the analytical ultracentrifuge a...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Phillips-Jones, Mary K., Lithgo, Ryan, Dinu, Vlad, Gillis, Richard B., Harding, John E., Adams, Gary G., Harding, Stephen E.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629194/
https://ncbi.nlm.nih.gov/pubmed/28983082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12620-z
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