Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis

By the age of 40, one in five adults without symptoms of cardiovascular disease are at risk for developing congestive heart failure. Within this population, dilated cardiomyopathy (DCM) remains one of the leading causes of disease and death, with nearly half of cases genetically determined. Though g...

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Udgivet i:PLoS Genet
Main Authors: Kennedy, Leslie, Kaltenbrun, Erin, Greco, Todd M., Temple, Brenda, Herring, Laura E., Cristea, Ileana M., Conlon, Frank L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629033/
https://ncbi.nlm.nih.gov/pubmed/28945738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007011
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