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The BMP pathway acts to directly regulate Tbx20 in the developing heart
TBX20 has been shown to be essential for vertebrate heart development. Mutations within the TBX20 coding region are associated with human congenital heart disease, and the loss of Tbx20 in a wide variety of model systems leads to cardiac defects and eventually heart failure. Despite the crucial role...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Company of Biologists
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867324/ https://ncbi.nlm.nih.gov/pubmed/20460370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.043588 |
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