The BMP pathway acts to directly regulate Tbx20 in the developing heart

TBX20 has been shown to be essential for vertebrate heart development. Mutations within the TBX20 coding region are associated with human congenital heart disease, and the loss of Tbx20 in a wide variety of model systems leads to cardiac defects and eventually heart failure. Despite the crucial role...

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Bibliografiske detaljer
Main Authors: Mandel, Elizabeth M., Kaltenbrun, Erin, Callis, Thomas E., Zeng, Xin-Xin I., Marques, Sara R., Yelon, Deborah, Wang, Da-Zhi, Conlon, Frank L.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2010
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867324/
https://ncbi.nlm.nih.gov/pubmed/20460370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.043588
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