Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis

By the age of 40, one in five adults without symptoms of cardiovascular disease are at risk for developing congestive heart failure. Within this population, dilated cardiomyopathy (DCM) remains one of the leading causes of disease and death, with nearly half of cases genetically determined. Though g...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Kennedy, Leslie, Kaltenbrun, Erin, Greco, Todd M., Temple, Brenda, Herring, Laura E., Cristea, Ileana M., Conlon, Frank L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629033/
https://ncbi.nlm.nih.gov/pubmed/28945738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007011
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