Microfluidic Transduction Harnesses Mass Transport Principles to Enhance Gene Transfer Efficiency

Ex vivo gene therapy using lentiviral vectors (LVs) is a proven approach to treat and potentially cure many hematologic disorders and malignancies but remains stymied by cumbersome, cost-prohibitive, and scale-limited production processes that cannot meet the demands of current clinical protocols fo...

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Dades bibliogràfiques
Publicat a:Mol Ther
Autors principals: Tran, Reginald, Myers, David R., Denning, Gabriela, Shields, Jordan E., Lytle, Allison M., Alrowais, Hommood, Qiu, Yongzhi, Sakurai, Yumiko, Li, William C., Brand, Oliver, Le Doux, Joseph M., Spencer, H. Trent, Doering, Christopher B., Lam, Wilbur A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628863/
https://ncbi.nlm.nih.gov/pubmed/28780274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.07.002
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