Microfluidic Transduction Harnesses Mass Transport Principles to Enhance Gene Transfer Efficiency

Ex vivo gene therapy using lentiviral vectors (LVs) is a proven approach to treat and potentially cure many hematologic disorders and malignancies but remains stymied by cumbersome, cost-prohibitive, and scale-limited production processes that cannot meet the demands of current clinical protocols fo...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther
Hoofdauteurs: Tran, Reginald, Myers, David R., Denning, Gabriela, Shields, Jordan E., Lytle, Allison M., Alrowais, Hommood, Qiu, Yongzhi, Sakurai, Yumiko, Li, William C., Brand, Oliver, Le Doux, Joseph M., Spencer, H. Trent, Doering, Christopher B., Lam, Wilbur A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628863/
https://ncbi.nlm.nih.gov/pubmed/28780274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.07.002
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