Augmentation of VAMP-catalytic activity of botulinum neurotoxin serotype B does not result in increased potency in physiological systems

Botulinum neurotoxins (BoNTs) are used extensively as therapeutic agents. Serotypes A and B are available as marketed products. Higher doses of BoNT/B are required to reach an efficacy similar to that of products containing BoNT/A. Advances in our understanding of BoNT/B mechanism of action have aff...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Elliott, Mark, Maignel, Jacquie, Liu, Sai Man, Favre-Guilmard, Christine, Mir, Imran, Farrow, Paul, Hornby, Fraser, Marlin, Sandra, Palan, Shilpa, Beard, Matthew, Krupp, Johannes
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628846/
https://ncbi.nlm.nih.gov/pubmed/28982136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185628
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items