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Botulinum Neurotoxins Serotypes A and B induce paralysis of mouse striated and smooth muscles with different potencies

To address the scarcity of direct comparison of botulinum neurotoxin serotypes activity on smooth versus striatal muscle, we have studied the action of BoNT/A1 and BoNT/B1 on ex vivo preparations of both muscle types. We have set up and characterized a model of neurogenic contractions in the isolate...

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Bibliografski detalji
Izdano u:Pharmacol Res Perspect
Glavni autori: Maignel‐Ludop, Jacquie, Huchet, Marion, Krupp, Johannes
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461647/
https://ncbi.nlm.nih.gov/pubmed/28596838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.289
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