High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors

NK cell education is the process through which chronic engagement of inhibitory NK cell receptors by self MHC-I molecules preserves cellular responsiveness. The molecular mechanisms responsible for NK cell education remain unclear. Here, we show that mouse NK cell education is associated with a high...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Marçais, Antoine, Marotel, Marie, Degouve, Sophie, Koenig, Alice, Fauteux-Daniel, Sébastien, Drouillard, Annabelle, Schlums, Heinrich, Viel, Sébastien, Besson, Laurie, Allatif, Omran, Bléry, Mathieu, Vivier, Eric, Bryceson, Yenan, Thaunat, Olivier, Walzer, Thierry
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2017
Onderwerpen:
Immunology and Inflammation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628014/
https://ncbi.nlm.nih.gov/pubmed/28875936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26423
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