High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors

NK cell education is the process through which chronic engagement of inhibitory NK cell receptors by self MHC-I molecules preserves cellular responsiveness. The molecular mechanisms responsible for NK cell education remain unclear. Here, we show that mouse NK cell education is associated with a high...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Marçais, Antoine, Marotel, Marie, Degouve, Sophie, Koenig, Alice, Fauteux-Daniel, Sébastien, Drouillard, Annabelle, Schlums, Heinrich, Viel, Sébastien, Besson, Laurie, Allatif, Omran, Bléry, Mathieu, Vivier, Eric, Bryceson, Yenan, Thaunat, Olivier, Walzer, Thierry
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2017
主題:
Immunology and Inflammation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628014/
https://ncbi.nlm.nih.gov/pubmed/28875936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26423
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