Ocular pharmacokinetics and tolerability of bimatoprost ophthalmic solutions administered once or twice daily in rabbits, and clinical dosing implications

PURPOSE: Fixed-combination medications can benefit patients requiring multiple agents to lower their intraocular pressure (IOP), but combining agents with complementary mechanisms of action is challenging if their dosing frequency differs. This study compares in vivo pharmacokinetic and ocular toler...

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Veröffentlicht in:Clin Ophthalmol
Hauptverfasser: Shen, Jie, Goodkin, Margot L, Tong, Warren, Attar, Mayssa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627754/
https://ncbi.nlm.nih.gov/pubmed/29026287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S143428
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