A Phase I and Pharmacokinetic Study of Oral Lapatinib Administered Once or Twice Daily in Patients with Solid Malignancies

PURPOSE: This study determined the range of tolerable doses, clinical safety, pharmacokinetics, and preliminary evidence of clinical activity following once or twice daily administration of lapatinib in patients with solid malignancies. EXPERIMENTAL DESIGN: Cancer patients (n = 81) received oral dos...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Burris, Howard A., Taylor, Charles W., Jones, Suzanne F., Koch, Kevin M., Versola, Melissa J., Arya, Niki, Fleming, Ronald A., Smith, Deborah A., Pandite, Lini, Spector, Neil, Wilding, George
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232441/
https://ncbi.nlm.nih.gov/pubmed/19825948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0369
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items