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Population Pharmacokinetic Study of Amikacin Administered Once or Twice Daily to Febrile, Severely Neutropenic Adults

Once-daily (o.d.) administration of 20 mg of amikacin per kg of body weight to neutropenic patients has been validated by clinical studies, but amikacin pharmacokinetics have been documented only for the 7.5-mg/kg twice-daily (b.i.d.) regimen in this population. In order to determine in neutropenic...

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Detalhes bibliográficos
Main Authors: Tod, Michel, Lortholary, Olivier, Seytre, Delphine, Semaoun, Rémi, Uzzan, Bernard, Guillevin, Loïc, Casassus, Philippe, Petitjean, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105554/
https://ncbi.nlm.nih.gov/pubmed/9559795
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