Population Pharmacokinetic Study of Amikacin Administered Once or Twice Daily to Febrile, Severely Neutropenic Adults

Once-daily (o.d.) administration of 20 mg of amikacin per kg of body weight to neutropenic patients has been validated by clinical studies, but amikacin pharmacokinetics have been documented only for the 7.5-mg/kg twice-daily (b.i.d.) regimen in this population. In order to determine in neutropenic...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Tod, Michel, Lortholary, Olivier, Seytre, Delphine, Semaoun, Rémi, Uzzan, Bernard, Guillevin, Loïc, Casassus, Philippe, Petitjean, Olivier
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Pharmacology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.849
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