Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies

Deficiency of interleukin (IL)-36 receptor antagonist (DITRA) syndrome is a rare autosomal recessive disease caused by mutations in IL36RN. IL-36R is a cell surface receptor and a member of the IL1R family that is involved in inflammatory responses triggered in skin and other epithelial tissues. Acc...

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Опубликовано в: :MAbs
Главные авторы: Ganesan, Rajkumar, Raymond, Ernest L., Mennerich, Detlev, Woska, Joseph R., Caviness, Gary, Grimaldi, Christine, Ahlberg, Jennifer, Perez, Rocio, Roberts, Simon, Yang, Danlin, Jerath, Kavita, Truncali, Kristopher, Frego, Lee, Sepulveda, Eliud, Gupta, Priyanka, Brown, Su-Ellen, Howell, Michael D., Canada, Keith A., Kroe-Barrett, Rachel, Fine, Jay S., Singh, Sanjaya, Mbow, M. Lamine
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2017
Предметы:
Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627585/
https://ncbi.nlm.nih.gov/pubmed/28726542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1353853
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