Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies

Deficiency of interleukin (IL)-36 receptor antagonist (DITRA) syndrome is a rare autosomal recessive disease caused by mutations in IL36RN. IL-36R is a cell surface receptor and a member of the IL1R family that is involved in inflammatory responses triggered in skin and other epithelial tissues. Acc...

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Publicado no:MAbs
Main Authors: Ganesan, Rajkumar, Raymond, Ernest L., Mennerich, Detlev, Woska, Joseph R., Caviness, Gary, Grimaldi, Christine, Ahlberg, Jennifer, Perez, Rocio, Roberts, Simon, Yang, Danlin, Jerath, Kavita, Truncali, Kristopher, Frego, Lee, Sepulveda, Eliud, Gupta, Priyanka, Brown, Su-Ellen, Howell, Michael D., Canada, Keith A., Kroe-Barrett, Rachel, Fine, Jay S., Singh, Sanjaya, Mbow, M. Lamine
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627585/
https://ncbi.nlm.nih.gov/pubmed/28726542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1353853
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