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Activation of Casein Kinase II by Gallic Acid Induces BIK–BAX/BAK-Mediated ER Ca(++)-ROS-Dependent Apoptosis of Human Oral Cancer Cells

Induction of the generation of endoplasmic reticulum (ER) calcium (Ca(++))-mediated reactive oxygen species (ROS) by gallic acid (GA) has been implicated in the mitochondrial apoptotic death of human oral cancer (OC) cells, but the molecular mechanism by which GA causes ER Ca(++) release of OC cells...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Lin, Meng-Liang, Chen, Shih-Shun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627504/
https://ncbi.nlm.nih.gov/pubmed/29033852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00761
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