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Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling

Angiogenesis plays an important role in hepatocellular carcinoma (HCC), the inhibition of which is explored for cancer prevention and treatment. The dietary phytochemical sulforaphane (SFN) is known for its anti-cancer properties in vitro and in vivo; but until now, no study has focused on the role...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Peng, Atkinson, Samuel J., Akbareian, Sophia E., Zhou, Zhigang, Munsterberg, Andrea, Robinson, Stephen D., Bao, Yongping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627255/
https://ncbi.nlm.nih.gov/pubmed/28978924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12855-w
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