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Mechanistic insights in X-chromosome inactivation

X-chromosome inactivation (XCI) is a critical epigenetic mechanism for balancing gene dosage between XY males and XX females in eutherian mammals. A long non-coding RNA (lncRNA), XIST, and its associated proteins orchestrate this multi-step process, resulting in the inheritable silencing of one of t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Philos Trans R Soc Lond B Biol Sci
Prif Awduron: Lu, Zhipeng, Carter, Ava C., Chang, Howard Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Royal Society 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627158/
https://ncbi.nlm.nih.gov/pubmed/28947655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0356
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