The Incorporation of Ribonucleotides Induces Structural and Conformational Changes in DNA

Ribonucleotide incorporation is the most common error occurring during DNA replication. Cells have hence developed mechanisms to remove ribonucleotides from the genome and restore its integrity. Indeed, the persistence of ribonucleotides into DNA leads to severe consequences, such as genome instabil...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Meroni, Alice, Mentegari, Elisa, Crespan, Emmanuele, Muzi-Falconi, Marco, Lazzaro, Federico, Podestà, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2017
Assuntos:
Nucleic Acids and Genome Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627062/
https://ncbi.nlm.nih.gov/pubmed/28978432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.07.013
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