The Incorporation of Ribonucleotides Induces Structural and Conformational Changes in DNA

Ribonucleotide incorporation is the most common error occurring during DNA replication. Cells have hence developed mechanisms to remove ribonucleotides from the genome and restore its integrity. Indeed, the persistence of ribonucleotides into DNA leads to severe consequences, such as genome instabil...

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Publicat a:Biophys J
Autors principals: Meroni, Alice, Mentegari, Elisa, Crespan, Emmanuele, Muzi-Falconi, Marco, Lazzaro, Federico, Podestà, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
Matèries:
Nucleic Acids and Genome Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627062/
https://ncbi.nlm.nih.gov/pubmed/28978432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.07.013
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