The Incorporation of Ribonucleotides Induces Structural and Conformational Changes in DNA

Ribonucleotide incorporation is the most common error occurring during DNA replication. Cells have hence developed mechanisms to remove ribonucleotides from the genome and restore its integrity. Indeed, the persistence of ribonucleotides into DNA leads to severe consequences, such as genome instabil...

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Bibliographic Details
Published in:Biophys J
Main Authors: Meroni, Alice, Mentegari, Elisa, Crespan, Emmanuele, Muzi-Falconi, Marco, Lazzaro, Federico, Podestà, Alessandro
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2017
Subjects:
Nucleic Acids and Genome Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627062/
https://ncbi.nlm.nih.gov/pubmed/28978432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.07.013
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