TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors

(E)-5-(Pyrimidin-5-yl)-1,2,3,4,7,8-hexahydroazocine (TC299423) is a novel agonist for nicotinic acetylcholine receptors (nAChRs). We examined its efficacy, affinity, and potency for α6β2(∗) (α6β2-containing), α4β2(∗), and α3β4(∗) nAChRs, using [(125)I]-epibatidine binding, whole-cell patch-clamp rec...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: Wall, Teagan R., Henderson, Brandon J., Voren, George, Wageman, Charles R., Deshpande, Purnima, Cohen, Bruce N., Grady, Sharon R., Marks, Michael J., Yohannes, Daniel, Kenny, Paul J., Bencherif, Merouane, Lester, Henry A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2017
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626944/
https://ncbi.nlm.nih.gov/pubmed/29033834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00641
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