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Small leucine rich proteoglycans, a novel link to osteoclastogenesis

Biglycan (Bgn) and Fibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP). In this study we examined the skeletal phenotype of BgnFmod double knockout (BgnFmod KO) mice and found they were smaller in size and have markedly reduced bone mass compared to WT. The low...

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Pubblicato in:Sci Rep
Autori principali: Kram, Vardit, Kilts, Tina M., Bhattacharyya, Nisan, Li, Li, Young, Marian F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626712/
https://ncbi.nlm.nih.gov/pubmed/28974711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12651-6
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