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The small leucine-rich proteoglycan BGN accumulates in CADASIL and binds to NOTCH3
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited form of cerebral small vessel disease caused by mutations in conserved residues of NOTCH3. Affected arteries of CADASIL feature fibrosis and accumulation of NOTCH3. A variety of colla...
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| Publicado no: | Transl Stroke Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359085/ https://ncbi.nlm.nih.gov/pubmed/25578324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-014-0379-1 |
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