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Small leucine rich proteoglycans, a novel link to osteoclastogenesis

Biglycan (Bgn) and Fibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP). In this study we examined the skeletal phenotype of BgnFmod double knockout (BgnFmod KO) mice and found they were smaller in size and have markedly reduced bone mass compared to WT. The low...

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Publicado en:Sci Rep
Autores principales: Kram, Vardit, Kilts, Tina M., Bhattacharyya, Nisan, Li, Li, Young, Marian F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626712/
https://ncbi.nlm.nih.gov/pubmed/28974711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12651-6
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