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Small leucine rich proteoglycans, a novel link to osteoclastogenesis

Biglycan (Bgn) and Fibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP). In this study we examined the skeletal phenotype of BgnFmod double knockout (BgnFmod KO) mice and found they were smaller in size and have markedly reduced bone mass compared to WT. The low...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kram, Vardit, Kilts, Tina M., Bhattacharyya, Nisan, Li, Li, Young, Marian F.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626712/
https://ncbi.nlm.nih.gov/pubmed/28974711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12651-6
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