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Small leucine rich proteoglycans, a novel link to osteoclastogenesis

Biglycan (Bgn) and Fibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP). In this study we examined the skeletal phenotype of BgnFmod double knockout (BgnFmod KO) mice and found they were smaller in size and have markedly reduced bone mass compared to WT. The low...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kram, Vardit, Kilts, Tina M., Bhattacharyya, Nisan, Li, Li, Young, Marian F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626712/
https://ncbi.nlm.nih.gov/pubmed/28974711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12651-6
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