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Small leucine rich proteoglycans, a novel link to osteoclastogenesis

Biglycan (Bgn) and Fibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP). In this study we examined the skeletal phenotype of BgnFmod double knockout (BgnFmod KO) mice and found they were smaller in size and have markedly reduced bone mass compared to WT. The low...

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Publicat a:Sci Rep
Autors principals: Kram, Vardit, Kilts, Tina M., Bhattacharyya, Nisan, Li, Li, Young, Marian F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626712/
https://ncbi.nlm.nih.gov/pubmed/28974711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12651-6
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