HNF1B loss exacerbates the development of chromophobe renal cell carcinomas

Chromophobe renal cell carcinoma (ChRCC) is characterized by major changes in chromosomal copy number (CN). No model is available to precisely elucidate the molecular drivers of this tumor type. HNF1B is a master regulator of gene expression. Here we report that the transcription factor HNF1B is dow...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Sun, Mianen, Tong, Pan, Kong, Wen, Dong, Baijun, Huang, Yiran, Park, Young, Zhou, Lijun, Liu, Xian-De, Ding, Zhiyong, Zhang, Xuesong, Bai, Shanshan, German, Peter, Powell, Reid, Wang, Quan, Tong, Xuefei, Tannir, Nizar M., Matin, Surena F., Rathmell, W. Kimryn, Fuller, Gregory N., McCutcheon, Ian E., Walker, Cheryl L., Wang, Jing, Jonasch, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626626/
https://ncbi.nlm.nih.gov/pubmed/28807937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0986
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