HNF1B loss exacerbates the development of chromophobe renal cell carcinomas

Chromophobe renal cell carcinoma (ChRCC) is characterized by major changes in chromosomal copy number (CN). No model is available to precisely elucidate the molecular drivers of this tumor type. HNF1B is a master regulator of gene expression. Here we report that the transcription factor HNF1B is dow...

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Udgivet i:Cancer Res
Main Authors: Sun, Mianen, Tong, Pan, Kong, Wen, Dong, Baijun, Huang, Yiran, Park, Young, Zhou, Lijun, Liu, Xian-De, Ding, Zhiyong, Zhang, Xuesong, Bai, Shanshan, German, Peter, Powell, Reid, Wang, Quan, Tong, Xuefei, Tannir, Nizar M., Matin, Surena F., Rathmell, W. Kimryn, Fuller, Gregory N., McCutcheon, Ian E., Walker, Cheryl L., Wang, Jing, Jonasch, Eric
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626626/
https://ncbi.nlm.nih.gov/pubmed/28807937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0986
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