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Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling
The mouse Langerhans cell (LC) network is established through the differentiation of embryonic LC precursors. BMP7 and TGFβ1 initiate cellular signaling that is essential for inducing LC differentiation and preserving LCs in a quiescent state, respectively. Here we show that loss of Cbfβ2, one of tw...
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| Pubblicato in: | J Exp Med |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626404/ https://ncbi.nlm.nih.gov/pubmed/28814567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170729 |
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