Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling

The mouse Langerhans cell (LC) network is established through the differentiation of embryonic LC precursors. BMP7 and TGFβ1 initiate cellular signaling that is essential for inducing LC differentiation and preserving LCs in a quiescent state, respectively. Here we show that loss of Cbfβ2, one of tw...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Tenno, Mari, Shiroguchi, Katsuyuki, Muroi, Sawako, Kawakami, Eiryo, Koseki, Keita, Kryukov, Kirill, Imanishi, Tadashi, Ginhoux, Florent, Taniuchi, Ichiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626404/
https://ncbi.nlm.nih.gov/pubmed/28814567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170729
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