Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer

Antiangiogenic therapy with antibodies against VEGF (bevacizumab) or VEGFR2 (ramucirumab) has been proven efficacious in colorectal cancer (CRC) patients. However, the improvement in overall survival is modest and only in combination with chemotherapy. Thus, there is an urgent need to identify poten...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jung, Keehoon, Heishi, Takahiro, Incio, Joao, Huang, Yuhui, Beech, Elizabeth Y., Pinter, Matthias, Ho, William W., Kawaguchi, Kosuke, Rahbari, Nuh N., Chung, Euiheon, Kim, Jun Ki, Clark, Jeffrey W., Willett, Christopher G., Yun, Seok Hyun, Luster, Andrew D., Padera, Timothy P., Jain, Rakesh K., Fukumura, Dai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625928/
https://ncbi.nlm.nih.gov/pubmed/28900008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710754114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados