Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

The recent approval of a prostate cancer vaccine has renewed hope for anticancer immunotherapies. However, the immunosuppressive tumor microenvironment may limit the effectiveness of current immunotherapies. Antiangiogenic agents have the potential to modulate the tumor microenvironment and improve...

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Detalhes bibliográficos
Main Authors: Huang, Yuhui, Yuan, Jianping, Righi, Elda, Kamoun, Walid S., Ancukiewicz, Marek, Nezivar, Jean, Santosuosso, Michael, Martin, John D., Martin, Margaret R., Vianello, Fabrizio, Leblanc, Pierre, Munn, Lance L., Huang, Peigen, Duda, Dan G., Fukumura, Dai, Jain, Rakesh K., Poznansky, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491458/
https://ncbi.nlm.nih.gov/pubmed/23045683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215397109
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