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Lis1 has two opposing modes of regulating cytoplasmic dynein
Regulation is central to the functional versatility of cytoplasmic dynein, a motor involved in intracellular transport, cell division, and neurodevelopment. Previous work established that Lis1, a conserved regulator of dynein, binds to its motor domain and induces a tight microtubule-binding state i...
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| Publicado en: | Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625841/ https://ncbi.nlm.nih.gov/pubmed/28886386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.037 |
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